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Impact of Social Isolation on Serum Sodium and Cortisol Level in male Wistar Rats

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Impact of Social Isolation on Serum Sodium and Cortisol Level in male Wistar Rats


Uzoma Reichmann Iheanyi | Ufearo Chibueze Steven | Njoku-Oji Nancy Njideka | Okonkwo Chukwudi Onyeka | Muorah Chinecherem Onyekachi | Umeasiegbu Adaobi Chidinma



Uzoma Reichmann Iheanyi | Ufearo Chibueze Steven | Njoku-Oji Nancy Njideka | Okonkwo Chukwudi Onyeka | Muorah Chinecherem Onyekachi | Umeasiegbu Adaobi Chidinma "Impact of Social Isolation on Serum Sodium and Cortisol Level in male Wistar Rats" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5, August 2021, pp.2044-2047, URL: https://www.ijtsrd.com/papers/ijtsrd46294.pdf

Background/Aim: Loneliness due to social isolation is a source of psychological stress in adults. This study evaluated the impact of social Isolation on serum sodium and cortisol level in male wistar ratsMethods: Sixteen male wistar rats were randomly divided into two groups (n = 8), Group 1 served as control. And were socially housed. Group 2; consisted of eight individually caged Wistar rats. The animals had access to food and water ad libitum and their level of physical activity was observed. After six weeks of Isolation, blood was collected from the animals via ocular puncture for Serum Cortisol and Sodium ion analysis, all data was analysed using SPSS software version 25.0. Values were considered significant at P < 0.05.Results: Results showed significant increase in the mean cortisol (33.82 ± 1.17), decrease in mean sodium ion (113.875 ± 5.24) and negative correlation between sodium and cortisol.Conclusion: The results from this study have shown that social isolation is a source of psychological stress which leads to depression and hyponatraemia.

Social Isolation, Stress, Sodium, Cortisol


IJTSRD46294
Volume-5 | Issue-5, August 2021
2044-2047
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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